"The narrator and protagonist, Calliope Stephanides (later called "Cal"), an intersexed person of Greek descent, has 5-alpha-reductase deficiency. The bulk of the novel is devoted to telling his coming-of-age story growing up in Detroit, Michigan in the late 20th century. This story, however, is intertwined with elements of a family saga, meditations on the era's zeitgeist and bits of contemporary history"